21st Century Medicine

hypothermic preservation, cryopreservation, Bio Logistics

preservationcryonics

21cm.com·Fontana, California, United States·

01Overview 02People 03Projects 04Concepts 05Patents 06Public records 07Belief evolution

Plate C · C-GAEO

Summary · Eternal Search editorial

21st Century Medicine hypothermic preservation, cryopreservation, Bio Logistics

21st Century Medicine has developed a platform technology focused on hypothermic preservation and cryopreservation techniques for living systems. Its work supports protection, preservation, transportation, storage, and future use across biopharmaceuticals, assisted reproductive technology, transplantation, and other bio-artificial applications. The company performs research testing and produces lab-scale cryopreservation solutions for research and educational purposes only.

The published score reflects a curated read of public evidence across 16 dimensions. Each dimension below shows the rationale we used. Disagree with a reading? Tell us where we are wrong →

Plate C·01 · Scientific profile

All 16 dimensions
on the record.

Composite32

Chain scale100 pts

Dimensions16

Plate C·02 · Where it sits among peers

Score vs. proximity
to longevity goals.

Higher up = higher Eternal Search score. Further right = closer to achieving real longevity outcomes (early mechanism → translational → near-term readout). Bubble size = capital deployed. Watch for MISMATCHES: big bubbles on the left are well-capitalized but far from goals; small bubbles on the right are doing more with less.

Reading

21st Century Medicine — Early mechanism · Lower middle. Derived deterministically from 8 extracted project(s). Most-advanced status: preclinical. Band: early_mechanism. Modifiers: +5 depth (6 programs at preclinical).…

Source: Deterministic

At a glance

Web21cm.com

HQFontana, California, United States

Publications

38 on file

012026Ultrastructural and Histological Cryopreservation of Mammalian Brains by VitrificationbioRxiv (Cold Spring Harbor Laboratory)→022026Electric fields for warming cryopreserved tissue.Cryobiology→03202555 MHz constant field dielectric warming of kidneys and ovaries cryopreserved by vitrification.Cryobiology→042024Biostasis: A Roadmap for Research in Preservation and Potential Revival of HumansBrain Sciences→052024Model biological systems demonstrate the inducibility of pathways that strongly reduce cryoprotectant toxicity.Cryobiology→06202427 MHz constant field dielectric warming of kidneys cryopreserved by vitrification.Cryobiology→072022The role of antifreeze glycoprotein (AFGP) and polyvinyl alcohol/polyglycerol (X/Z-1000) as ice modulators during partial freezing of rat liversFrontiers in Physics→082021The role of antifreeze glycopeptides (AFGP) and polyvinyl alcohol/polyglycerol (X/Z-1000) cocktails as ice modulators during partial freezing of rat liversbioRxiv (Cold Spring Harbor Laboratory)→092021Principles of Ice-Free Cryopreservation by Vitrification.Methods in molecular biology (Clifton, N.J.)→102021Vitrification and Nanowarming of KidneysAdvanced Science→112020Imaging the distribution of iron oxide nanoparticles in hypothermic perfused tissues.Magnetic resonance in medicine→122019Genetic suppression of cryoprotectant toxicity.Cryobiology→132018Vitrification tendency and stability of DP6-based vitrification solutions for complex tissue cryopreservation.Cryobiology→142017Thermal Analyses of a Human Kidney and a Rabbit Kidney During Cryopreservation by VitrificationJournal of Biomechanical Engineering→152017The promise of organ and tissue preservation to transform medicineNature Biotechnology→162016The Grand Challenges of Organ Banking: Proceedings from the first global summit on complex tissue cryopreservation.Cryobiology→172015Validation of microSecure vitrification (μS-VTF) for the effective cryopreservation of human embryos and oocytes.Cryobiology→18201530. Roles of ice-active agents in organ cryopreservationCryobiology→192015Aldehyde-stabilized cryopreservation.Cryobiology→202015Insights on cryoprotectant toxicity from gene expression profiling of endothelial cells exposed to ethylene glycol.Cryobiology→212015Principles of cryopreservation by vitrification.Methods in molecular biology (Clifton, N.J.)→222014The future of death.Journal of critical care→232013Cryopreservation of precision-cut tissue slices.Xenobiotica; the fate of foreign compounds in biological systems→242010Cryoprotectant toxicity neutralization.Cryobiology→252010Armand M. Karow, Jr.: Looking back.Cryobiology→262010Thermodynamic aspects of vitrification.Cryobiology→272009Microsecure vitrification (MS-VTF): simple, safe, sterile, secure and clinically successfulFertility and Sterility→282009WITHDRAWN: Thermodynamic aspects of vitrification.Cryobiology→292007Theoretical considerations for oocyte cryopreservation by freezing.Reproductive biomedicine online→302006Cryopreservation of complex systems: the missing link in the regenerative medicine supply chain.Rejuvenation research→312005Anomalous high activity of a subfraction of polyvinyl alcohol ice blocker.Cryobiology→322004Erratum to “Improved vitrification solutions based on the predictability of vitrification solution toxicity” [Cryobiology 48 (2004) 22–35]Cryobiology→332004Improved vitrification solutions based on the predictability of vitrification solution toxicity.Cryobiology→342004Cryopreservation of organs by vitrification: perspectives and recent advances.Cryobiology→352003Ultrarapid nonsuture mated cuff technique for renal transplantation in rabbits.Microsurgery→362002Inhibition of bacterial ice nucleation by polyglycerol polymers.Cryobiology→372000Vitrification enhancement by synthetic ice blocking agents.Cryobiology→381999Effects of solute methoxylation on glass-forming ability and stability of vitrification solutions.Cryobiology→

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0-100 chain-logic scale · 15 dimensions · scored on public evidence

21st Century Medicine

All 16 dimensionson the record.

Score vs. proximityto longevity goals.

Publications

Loading

All 16 dimensionson the record.

Score vs. proximityto longevity goals.

Publications

All 16 dimensions
on the record.

Score vs. proximity
to longevity goals.

All 16 dimensions
on the record.

Score vs. proximity
to longevity goals.