Live·Open questions in longevity research
Omega Point · Lab

Omega Point runs

Every run started from the workbench, recorded the moment it starts. A run that stops at the step you switched off is finished, not interrupted. The autopilot column says where the run's hypotheses stand: waiting for their titles, being checked for duplicates, or done and moving one by one to publication.

StartedGoalStatusStepYieldElapsed (min)Autopilot
2026-09-20 22:32In people with age-related immune dysfunction, what conditions are necessary and jointly sufficient to durably restore key functions of innate and adaptive immunity to levels within the ranges observed in healthy young adults, while preserving protective immunological memory, self-tolerance, and control of latent infections? completed at the chosen stepfinished after step 8: Resuming
2026-09-20 22:32
nothing producedDuplicate check done
0 waiting · 49 approved · 0 published · 1 duplicates
2026-09-20 20:53In people with age-related immune dysfunction, what conditions are necessary and jointly sufficient to durably restore key functions of innate and adaptive immunity to levels within the ranges observed in healthy young adults, while preserving protective immunological memory, self-tolerance, and control of latent infections? interrupted8: Tactical decomposition
20 gap questions
heartbeat 2026-09-20 22:32
nothing produced99.2no hypotheses yet
2026-09-20 16:19How to avoid immunogenity of the transplanted tissues completely without suppressing immune system?completed at the chosen stepfinished after step 7: Hypothesis instantiation
2026-09-20 17:17
nothing produced58.2Manual (run predates the autopilot)
53 waiting · 0 approved · 0 published · 1 duplicates
2026-09-19 19:44What is the minimum amount of tissue should be replaced and exactly which parts of the tissues, what cells or areas or intercellular structures and which tissues need to be replaced to slow down aging and extend lifespan?completed at the chosen stepfinished after step 7: Hypothesis instantiation
2026-09-19 20:23
nothing produced39.6Manual (run predates the autopilot)
0 waiting · 33 approved · 12 published · 2 duplicates
2026-09-16 20:46What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?completed at the chosen stepfinished after step 7: Hypothesis instantiation
2026-09-16 22:50
nothing produced124.3Manual (run predates the autopilot)
80 waiting · 0 approved · 20 published
2026-09-16 19:38What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?interrupted4: Reality mapping (domain scan)
4 goals
heartbeat 2026-09-16 20:44
nothing produced66no hypotheses yet
2026-09-16 16:19What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?completed at the chosen stepfinished after step 7: Hypothesis instantiation
2026-09-16 19:02
nothing produced163.5Manual (run predates the autopilot)
100 waiting · 0 approved · 0 published
2026-09-16 15:28How to rejuvenate the stem cell niche?interrupted
test
9: Execution drilldown
4 discriminating questions
heartbeat 2026-09-16 15:33
nothing produced5.2no hypotheses yet
2026-09-16 15:22What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?completed at the chosen stepfinished after step 2: Goal pillars synthesis
2026-09-16 15:25
nothing produced3.1no hypotheses yet
2026-09-16 13:57How to rejuvenate the stem cell niche?completed at the chosen stepfinished after step 2: Goal pillars synthesis
2026-09-16 13:59
nothing produced2.7no hypotheses yet
2026-09-16 13:47What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?completed at the chosen stepfinished after step 2: Goal pillars synthesis
2026-09-16 13:50
nothing produced3no hypotheses yet
2026-09-16 13:36What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?completed at the chosen stepfinished after step 2: Goal pillars synthesis
2026-09-16 13:39
nothing produced3.1no hypotheses yet
2026-09-16 13:21What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?interrupted4: Reality mapping (domain scan)
4 goals
heartbeat 2026-09-16 13:35
nothing produced14no hypotheses yet
2026-09-16 01:03What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?interrupted7: Hypothesis instantiation
20 gap questions
heartbeat 2026-09-16 02:06
0 goal pillars
20 gaps
0 L6 tasks
0 selected
62.9Manual (run predates the autopilot)
120 waiting · 0 approved · 0 published
2026-09-15 23:53What is the minimum amount of tissue—and exactly which parts—that needs to be replaced to slow down aging and extend lifespan?interrupted7: Hypothesis instantiation
20 gap questions
heartbeat 2026-09-16 00:59
nothing produced66.1no hypotheses yet
2026-09-13 23:27How to rejuvenate the stem cell niche?interrupted
test
9: Execution drilldown
4 discriminating questions
heartbeat 2026-09-13 23:27
nothing produced0.1Manual (run predates the autopilot)
0 waiting · 0 approved · 5 published
2026-09-13 23:07How to rejuvenate the stem cell niche?interrupted
test
9: Execution drilldown
4 discriminating questions
heartbeat 2026-09-13 23:20
nothing produced13.1no hypotheses yet
2026-09-13 22:56How to rejuvenate the stem cell niche?interrupted
test
8: Tactical decomposition
1 gap questions
heartbeat 2026-09-13 23:04
nothing produced7.7no hypotheses yet
2026-09-13 22:27How to rejuvenate the stem cell niche?interrupted
test
4: Reality mapping (domain scan)
1 goals
heartbeat 2026-09-13 22:43
nothing produced16no hypotheses yet
2026-09-13 21:36How to rejuvenate the stem cell niche?interrupted
test
4: Reality mapping (domain scan)
1 goals
heartbeat 2026-09-13 21:38
nothing produced1.8no hypotheses yet
2026-09-13 20:57How to rejuvenate the stem cell niche?interrupted
test
4: Reality mapping (domain scan)
1 goals
heartbeat 2026-09-13 21:11
nothing produced14.8no hypotheses yet
2026-09-13 20:46How to rejuvenate the stem cell niche?interrupted
test
3: Requirement atomization
1 goals
heartbeat 2026-09-13 20:50
nothing produced3.8no hypotheses yet
2026-09-13 19:55How to rejuvenate the stem cell niche?interrupted
test
2: Goal pillars synthesis
heartbeat 2026-09-13 20:00
nothing produced5.2no hypotheses yet
2026-09-13 19:39How to rejuvenate the stem cell niche?interrupted
test
2: Goal pillars synthesis
heartbeat 2026-09-13 19:46
nothing produced6.4no hypotheses yet
2026-09-13 19:03How to rejuvenate the stem cell niche?failed at execute
test
2026-09-13 19:04nothing produced1.2no hypotheses yet
2026-09-13 18:48How to rejuvenate the stem cell niche?failed at execute
test
2026-09-13 18:48nothing produced0.4no hypotheses yet
2026-09-13 14:43How to rejuvenate the stem cell niche?interrupted9: Repairing the explanatory record
Idea 4, repair 2/2
heartbeat 2026-09-13 15:23
nothing produced40.5no hypotheses yet
2026-09-13 13:49How to rejuvenate the stem cell niche?interrupted9: Repairing the explanatory record
Idea 5, repair 1/2
heartbeat 2026-09-13 14:43
nothing produced53.6no hypotheses yet
2026-09-13 12:09How to rejuvenate the stem cell niche?interrupted9: Checking evidence and reasoning
Idea 5/6
heartbeat 2026-09-13 13:49
nothing produced100.1no hypotheses yet
2026-09-13 11:21How to rejuvenate the stem cell niche?interrupted9: Repairing the explanatory record
Idea 3, repair 1/2
heartbeat 2026-09-13 12:09
nothing produced47.6no hypotheses yet
2026-09-13 10:19How to rejuvenate the stem cell niche?interrupted9: Repairing the explanatory record
Idea 3, repair 1/2
heartbeat 2026-09-13 11:21
nothing produced61.5no hypotheses yet
2026-09-13 08:11How to rejuvenate the stem cell niche?interrupted9: Repairing the explanatory record
Idea 2, repair 1/2
heartbeat 2026-09-13 10:19
nothing produced127.6no hypotheses yet
2026-09-13 07:26How to rejuvenate the stem cell niche?interrupted9: Checking evidence and reasoning
Idea 2/6
heartbeat 2026-09-13 08:10
nothing produced44no hypotheses yet
2026-09-13 06:54How to rejuvenate the stem cell niche?interrupted9: Checking evidence and reasoning
Idea 2/6
heartbeat 2026-09-13 07:26
nothing produced32no hypotheses yet
2026-09-13 06:06How to rejuvenate the stem cell niche?interrupted9: Repairing the explanatory record
Idea 2, repair 2/2
heartbeat 2026-09-13 06:53
nothing produced47no hypotheses yet
2026-09-13 05:17How to rejuvenate the stem cell niche?interrupted9: Repairing the explanatory record
Idea 1, repair 1/2
heartbeat 2026-09-13 06:05
nothing produced48.5no hypotheses yet
2026-09-13 04:47How to rejuvenate the stem cell niche?interrupted9: Checking evidence and reasoning
Idea 3/6
heartbeat 2026-09-13 05:16
nothing produced29no hypotheses yet
2026-09-13 01:56How to rejuvenate the stem cell niche?interrupted9: Checking evidence and reasoning
Idea 1/6
heartbeat 2026-09-13 04:46
nothing produced170.7no hypotheses yet
2026-09-13 00:36How to rejuvenate the stem cell niche?interrupted6: Developing explanatory ideas
heartbeat 2026-09-13 01:52
nothing produced76.1no hypotheses yet
2026-09-12 22:44How might circadian timing affect age-related inflammatory responses? Develop competing explanatory ideas.completed
test
2026-09-12 22:55
1 goal pillars
1 gaps
2 L6 tasks
2 selected
9.7no hypotheses yet
2026-09-12 22:38How might circadian timing affect age-related inflammatory responses? Develop competing explanatory ideas.failed at execute
test
2026-09-12 22:40nothing producedno hypotheses yet
2026-09-12 22:27How might circadian timing affect age-related inflammatory responses? Develop competing explanatory ideas.failed at execute
test
2026-09-12 22:35nothing producedno hypotheses yet
2026-09-12 22:18How might circadian timing affect age-related inflammatory responses? Develop competing explanatory ideas.failed at execute
test
2026-09-12 22:18nothing producedno hypotheses yet
2026-09-12 02:01How to make immune system work for rejuvenationcompleted2026-09-12 18:54
4 goal pillars
20 gaps
401 L6 tasks
0 selected
1013.5Manual (run predates the autopilot)
120 waiting · 0 approved · 0 published
2026-09-10 21:37Radical life extension of human life spanfailed at execute2026-09-11 00:14nothing produced156.9no hypotheses yet
2026-09-10 00:48Radical life extension of human life spanfailed at execute2026-09-10 02:46nothing produced117no hypotheses yet
2026-09-08 12:06I would frame your research objective as follows: identify a slowly changing physical state on which an organism’s ability to recreate the conditions necessary for its own functioning depends. completed2026-09-08 14:53
4 goal pillars
15 gaps
48 L6 tasks
11 selected
167.4Manual (run predates the autopilot)
75 waiting · 0 approved · 0 published
2026-09-08 12:05Radical life extension of human life spancompleted2026-09-08 15:02
4 goal pillars
20 gaps
60 L6 tasks
5 selected
176.7Manual (run predates the autopilot)
99 waiting · 0 approved · 1 published
2026-09-07 23:19Radical life extension of human life spancompleted2026-09-08 02:31
4 goal pillars
20 gaps
41 L6 tasks
11 selected
192.5Manual (run predates the autopilot)
100 waiting · 0 approved · 0 published
2026-09-07 00:44We need a way for stable creation new organs and tissues for the replacement of the damaged or unfunctional tissues in the human bodycompleted2026-09-07 00:44
4 goal pillars
20 gaps
30 L6 tasks
3 selected
185.1Manual (run predates the autopilot)
100 waiting · 0 approved · 0 published
2026-09-07 00:44Radical life extension of human life spancompleted2026-09-07 00:44
4 goal pillars
20 gaps
42 L6 tasks
3 selected
236.5Manual (run predates the autopilot)
100 waiting · 0 approved · 0 published
2026-09-07 00:44Radical life extension of human life spancompleted2026-09-07 00:44
4 goal pillars
20 gaps
6 L6 tasks
3 selected
265.9Manual (run predates the autopilot)
95 waiting · 0 approved · 0 published
2026-09-06 16:25We need a way for stable creation new organs and tissues for the replacement of the damaged or unfunctional tissues in the human bodycompleted2026-09-06 16:25
4 goal pillars
20 gaps
18 L6 tasks
11 selected
186.3Manual (run predates the autopilot)
100 waiting · 0 approved · 0 published