Scale or classification
Treatment response classification
Grouping participants according to their response to treatment
Hypotheses on this target 1
Telling states apart1
Direct measurement
Indicator replacement
Telling states apart1
Selection by itch relief may create the apparent benefit of removing skin irritants
Where this hypothesis actsComparisons of interventions with equal itch reduction in participants with skin damage
What is proposedDescribe itch reduction as an outcome without using it as the sole inclusion criterion
With whatNot stated in the record
HowAssign interventions before treatment, analyse all enrolled participants, and compare with analyses restricted to participants with equal itch reduction
Possible resultExpected equivalence in warning timing and protective time margin when all enrolled participants are analysed
2026-09-25