Fibroblast or stromal cell
Stromal cells
Cells that contribute to the maintenance and repair of the surrounding tissue environment
Hypotheses on this target 1
Senomorphic suppression
Reprogramming
Transplantation
Elimination
Population balance1
Population balance1
Selection against repair-contributing stromal cells may sustain damage across tissues
Where this hypothesis actsAgeing stroma with heritable differences in repair contribution and damage sustained across tissues
What is proposedShift the population balance above the threshold favouring repair-contributing cells
With whatNot stated in the record
HowBriefly change relative cell survival in one component of the intertissue system to raise the proportion of repair-contributing cells above the threshold
Possible resultPossible sustained repair in both tissues through selection favouring repair-contributing cells
2026-09-30