Lipid
Specialized pro-resolving lipid mediators
Lipid mediators whose production supports the resolution of inflammatory activity
Hypotheses on this target 2
Lower level
Neutralisation
Supplementation1
Composition restoration
Supplementation1
Restoring skin matrix makes faster drainage wash away signals needed for recovery
Where this hypothesis actsMatrix-restored aged skin under increased lymphatic drainage
What is proposedPreserve local resolving-mediator exposure
With whatSmall molecule
HowReplace the selectively depleted mediator to reproduce its low-drainage tissue concentration-time profile while drainage remains high
Possible resultPossible restoration of inflammatory resolution and barrier recovery despite increased drainage
2026-09-21