Live·Open questions in longevity research

Signalling molecule

Senescent-cell secretions

Substances released by senescent cells that can alter signaling in other cells

Hypotheses on this target 1

Senescent-cell secretionsLower level. Hypotheses on this target 11Synthesis suppression. Hypotheses on this target 0Neutralisation. Hypotheses on this target 0Supplementation. Hypotheses on this target 0Accelerated excretion. Hypotheses on this target 0
  • Lower level1
  • Synthesis suppression
  • Neutralisation
  • Supplementation
  • Accelerated excretion

Lower level1

  • Senescent-cell secretions change lymphatic pumping and determine when suppression helps

    Where this hypothesis actsAfter infection, near collecting lymphatics with different neuropeptide-dependent contractile states

    What is proposedSuppress senescent-cell secretions locally

    With whatNot stated in the record

    HowLocal secretome suppression; the suppression technique is not stated in the record

    Possible resultPossible rapid changes in lymphatic pumping, with benefit or harm depending on the contractile state

    2026-09-17