Live·Open questions in longevity research
All targets

Rhythm or programme

Ribosome assembly

The process of assembling ribosomal proteins and ribosomal RNA into ribosomes

Hypotheses on this target 1

Ribosome assemblyInhibition. Hypotheses on this target 0Activation. Hypotheses on this target 0Function preservation. Hypotheses on this target 0Feedback restoration. Hypotheses on this target 0Rhythm restoration. Hypotheses on this target 11Direct measurement. Hypotheses on this target 0
  • Inhibition
  • Activation
  • Function preservation
  • Feedback restoration
  • Rhythm restoration1
  • Direct measurement

Rhythm restoration1

  • Mismatched ribosome assembly may make muscle recovery limit fasting-mimetic lifespan gains

    Where this hypothesis actsIn old muscle when ribosomal protein synthesis resumes ahead of ribosomal RNA maturation

    What is proposedCoordinate ribosomal protein synthesis with ribosomal RNA maturation

    With whatNot stated in the record

    HowA means of selectively coordinating ribosome assembly in old muscle remains to be developed

    Possible resultPossible prevention of proteotoxicity while preserving the amplitude of the anabolic surge

    2026-10-06