Live·Open questions in longevity research

Metabolite or ion

Potassium

An intracellular and circulating ion whose tissue stores can decline despite normal plasma levels

Hypotheses on this target 2

PotassiumSupplementation. Hypotheses on this target 11Accelerated excretion. Hypotheses on this target 0Composition restoration. Hypotheses on this target 0

Supplementation1

  • Potassium loss after muscle restoration causes failure during the next bout of activity

    Where this hypothesis actsIn aged animals undergoing repeated activity challenges after muscle restoration or sham treatment

    What is proposedRestore potassium balance by replacing measured losses

    With whatNot stated in the record

    HowReplace measured potassium losses within prespecified physiological bounds

    Possible resultExpected recovery of urea-production capacity and fewer next-episode ECG and cognitive abnormalities

    2026-09-20