Receptor or channel
Peptide–MHC complexes
Peptide–MHC complexes are cell-surface complexes recognized by T cells
Hypotheses on this target 1
Lower level
Higher level
Blockade1
Agonism
Desensitisation
Function restoration
Function preservation
Blockade1
Borrowed familiar targets make recall immune cells kill unrelated new immune cells
Where this hypothesis actsAcquired familiar complexes on newly activated unfamiliar-specificity CD8 cells while recall cytotoxic cells are active
What is proposedBlock recall-cell recognition of acquired familiar peptide–MHC complexes
With whatNot stated in the record
HowSelectively mask acquired familiar complexes on recipient unfamiliar-specificity cells while retaining established recall protection
Possible resultPossible restoration of unfamiliar-cell post-contraction persistence and target-specific killing
2026-09-21