Live·Open questions in longevity research

Metabolism and energy

Nutrient uptake and metabolism

The uptake and metabolic use of nutrients for biomass production, energy or cellular maintenance

Hypotheses on this target 1

Nutrient uptake and metabolismInhibition. Hypotheses on this target 11Activation. Hypotheses on this target 0Function preservation. Hypotheses on this target 0Supplementation. Hypotheses on this target 0Feedback restoration. Hypotheses on this target 0Direct measurement. Hypotheses on this target 0
  • Inhibition1
  • Activation
  • Function preservation
  • Supplementation
  • Feedback restoration
  • Direct measurement

Inhibition1

  • Dead resident cells may feed invasive lineages during epithelial repair

    Where this hypothesis actsPre-existing invasive epithelial lineages during repair in aging human epithelium

    What is proposedSelectively interrupt uptake or metabolic use of material released by resident cell death

    With whatNot stated in the record

    HowIdentify a limiting substrate, then perturb invader-specific uptake or conversion, verify flux loss and test pathway or suitable nutrient rescue

    Possible resultExpected reduction in extra survival or production if death-derived material causally supports it

    2026-10-10