Signalling pathway
Neurogenic vasodilation
A nerve-mediated vascular response that increases blood flow
Hypotheses on this target 1
Inhibition1
Activation
Desensitisation
Function preservation
Feedback restoration
Rhythm restoration
Inhibition1
Weak backup blood flow may leave treated skin vulnerable when nerve-driven responses fade
Where this hypothesis actsSeparate mechanistic tests in treated and young skin
What is proposedPartially suppress the neurogenic vascular pathway to test dependence on it
With whatSmall molecule
HowPharmacological separation of vascular mechanisms at separate skin sites, with controls for the intervention's own effects
Possible resultExpected greater impairment of the vascular response in treated skin than in young skin
2026-09-25