Indicator or biomarker
Mitotically reactivatable infected cell count
The number of infected cells that yield viable bacteria after a standardized mitotic challenge
Hypotheses on this target 1
Telling states apart
Direct measurement1
Indicator replacement
Direct measurement1
Host cell division enables dormant bacteria to awaken in some mucosal infections
Where this hypothesis actsOlder-donor urothelial cultures undergoing repair during intracellular bacterial infection
What is proposedQuantify mitotically reactivatable infected cells to estimate the repair threshold
With whatInstrument or assay
HowCount cells yielding viable bacteria after a standardized mitotic challenge and test prediction of rebound beyond total CFU
Possible resultPossible identification of a threshold below which accelerated repair is protective
2026-09-21