Live·Open questions in longevity research

Rhythm or programme

Mitotic entry in basal keratinocytes

Entry into mitosis by basal keratinocytes during skin recovery

Hypotheses on this target 1

Mitotic entry in basal keratinocytesInhibition. Hypotheses on this target 11Activation. Hypotheses on this target 0Function preservation. Hypotheses on this target 0Feedback restoration. Hypotheses on this target 0Rhythm restoration. Hypotheses on this target 0Direct measurement. Hypotheses on this target 0
  • Inhibition1
  • Activation
  • Function preservation
  • Feedback restoration
  • Rhythm restoration
  • Direct measurement

Inhibition1

  • Synchronized skin cell division may let wet friction cause lasting damage through chromosome errors

    Where this hypothesis actsRecovering organotypic skin models from donors aged 40–60 years under wet mechanical load

    What is proposedBriefly and reversibly delay entry into mitosis

    With whatNot stated in the record

    HowUse independent temporary interventions, fully stopped before subsequent recovery; specific interventions are not stated

    Possible resultPossible reduction in delayed damage under the same load, despite slower early closure

    2026-09-25