Live·Open questions in longevity research

Mechanics and load

Mechanical loading

The application of mechanical forces to a structure

Hypotheses on this target 1

Mechanical loadingInhibition. Hypotheses on this target 0Activation. Hypotheses on this target 0Function preservation. Hypotheses on this target 0Remodelling. Hypotheses on this target 0Load normalisation. Hypotheses on this target 11Direct measurement. Hypotheses on this target 0

Load normalisation1

  • Rare structural defects may trigger the first cracks at dried skin boundaries

    Where this hypothesis actsAt critical microregions along the boundary of an unevenly dried stratum corneum during bending

    What is proposedReduce local loading below individual defect failure thresholds

    With whatNot stated in the record

    HowAccelerating relaxation is proposed as a possible way to reduce stress, without a universal protective τ/T value

    Possible resultPossible prevention of failure at critical microregions and the first edge crack

    2026-09-25