Immune cell
Mast cells
Immune cells capable of inflammatory secretion and mechanically evoked ATP release
Hypotheses on this target 1
Activation
Clearance restoration
Reprogramming
Adoptive transfer
Elimination
Immunosuppression1
Population balance
Immunosuppression1
Aged skin depends on mast cells to warn of pressure injury
Where this hypothesis actsAged, photoexposed skin under sustained low-grade pressure
What is proposedSelectively suppress neuropeptide-triggered inflammatory secretion
With whatNot stated in the record
HowSelective mast-cell modulation; separating inflammatory secretion from mechanically evoked ATP release remains an experimental requirement
Possible resultPossible preservation of perfusion without loss of protective warning or recovery
2026-09-21