Rhythm or programme
Lysosomal exocytosis
A process through which cells expel material from lysosomes into the extracellular space
Hypotheses on this target 1
Inhibition
Activation1
Function preservation
Feedback restoration
Rhythm restoration
Direct measurement
Activation1
Expelling lysosomal waste may restore lasting repair without sustained nuclear rejuvenation
Where this hypothesis actsA prospectively defined subset of aging human dermal fibroblast lineages under fixed extracellular-disposal conditions
What is proposedIncrease export of chemically persistent lysosomal residual bodies
With whatNot stated in the record
HowRepeated partial reprogramming, with selective export blockade, specific export rescue and export-alone comparisons; intervention details require calibration
Possible resultPossible durable recovery of fibroblast function after factor withdrawal through repeated repair
2026-10-10