Live·Open questions in longevity research
All targets

Enzyme

Intestinal alkaline phosphatase

An intestinal enzyme that dephosphorylates bacterial proinflammatory components

Hypotheses on this target 1

Intestinal alkaline phosphataseInhibition. Hypotheses on this target 0Activation. Hypotheses on this target 0Lower level. Hypotheses on this target 0Higher level. Hypotheses on this target 0Replacement. Hypotheses on this target 11Protection from degradation. Hypotheses on this target 0Cofactor removal. Hypotheses on this target 0Synthesis suppression. Hypotheses on this target 0Function preservation. Hypotheses on this target 0
  • Inhibition
  • Activation
  • Lower level
  • Higher level
  • Replacement1
  • Protection from degradation
  • Cofactor removal
  • Synthesis suppression
  • Function preservation

Replacement1

  • Restoring intestinal alkaline phosphatase may limit pathological growth after regeneration

    Where this hypothesis actsIntestinal contents during epithelial maturation after repair

    What is proposedRestore intestinal alkaline phosphatase activity

    With whatProtein or peptide as the agent

    HowAdminister recombinant intestinal alkaline phosphatase protected from degradation during stomach passage, during epithelial maturation

    Possible resultPossible reduction in inflammatory damage and later pathological clone expansion, contributing to longer life

    2026-10-05