Live·Open questions in longevity research

Signalling molecule

Interleukin-1 receptor antagonist

A protein that antagonizes interleukin-1 receptor signalling

Hypotheses on this target 2

Interleukin-1 receptor antagonistLower level. Hypotheses on this target 0Synthesis suppression. Hypotheses on this target 0Neutralisation. Hypotheses on this target 0Supplementation. Hypotheses on this target 0Accelerated excretion. Hypotheses on this target 11

Accelerated excretion1

  • Cytokine binding in dead skin cells may store the order of wetting and friction

    Where this hypothesis actsBound and available forms in nonliving corneocytes after different sequences of hydration and friction

    What is proposedSelectively eliminate its contribution to the proposed biochemical memory

    With whatRemoval from a body fluid

    HowImmunodeplete it together with interleukin-1α from extracts, then restore the measured protein ratio for each exposure sequence to test recovery of transfer

    Possible resultExpected loss of memory transfer, with transfer returning after restoration of the sequence-specific protein ratio

    2026-09-26