Immune response
Immune surveillance
The immune response that recognizes and removes target cells through cytotoxic activity
Hypotheses on this target 1
Inhibition
Activation
Function preservation
Clearance restoration1
Immunosuppression
Feedback restoration
Rhythm restoration
Clearance restoration1
Delayed immune clearance may drive recurring waves of senescent cells and tissue damage
Where this hypothesis actsIn linked tissue models after removal of chronically senescent cells
What is proposedShorten the delay between senescent cell emergence and effective immune clearance
With whatChange of environment or regimen
HowControl the timing of contact with cytotoxic cells while keeping total contact numbers and effectiveness per contact comparable
Possible resultPossible stabilization of SPV_2 and dampening of recurrent senescence and damage across tissues
2026-09-30