Signalling molecule
Fas ligand
A ligand that can trigger apoptosis in cells encountering it
Hypotheses on this target 1
Lower level
Synthesis suppression
Neutralisation1
Supplementation
Accelerated excretion
Neutralisation1
The blood vessel lining kills protective immune cells as they enter tissue
Where this hypothesis actsAt the endothelial interface of the implicated tissue, where arriving protective effector cells undergo apoptosis
What is proposedInterrupt endothelial Fas ligand activity
With whatNot stated in the record
HowEndothelial-restricted FasL interruption; the specific intervention is not stated in the record
Possible resultPossible restoration of viable effector cell entry and local pathogen control using existing circulating specificities
2026-09-21