Structural protein
Dermal collagen I and III triple helices
Triple-helical structural proteins in dermal collagen fibres that bear mechanical loads
Hypotheses on this target 1
Lower level
Higher level
Replacement
Protection from degradation
Function preservation1
Remodelling
Crosslink prevention
Function preservation1
Irreversible collagen unfolding may limit repeated shear tolerance after anchoring fibril repair
What is proposedReduce the probability of irreversible molecular unfolding under repeated shear
With whatNot stated in the record
HowNot stated in the record
2026-09-25