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All targets

Structural protein

Collagen IV

A structural protein that forms part of the basement membrane network

Hypotheses on this target 1

Collagen IVLower level. Hypotheses on this target 0Higher level. Hypotheses on this target 0Replacement. Hypotheses on this target 0Protection from degradation. Hypotheses on this target 0Function preservation. Hypotheses on this target 0Remodelling. Hypotheses on this target 11Crosslink prevention. Hypotheses on this target 0
  • Lower level
  • Higher level
  • Replacement
  • Protection from degradation
  • Function preservation
  • Remodelling1
  • Crosslink prevention

Remodelling1

  • Neutrophil myeloperoxidase may strengthen healing skin by crosslinking new basement membrane

    Where this hypothesis actsUncrosslinked regions of the assembling basement membrane in healing skin with insufficient peroxidasin activity

    What is proposedPromote maturation by forming sulfilimine crosslinks

    With whatNot stated in the record

    HowAllow neutrophil myeloperoxidase to access collagen IV regions before their incorporation into a dense network

    Possible resultPossible stronger epidermal attachment and earlier resistance to shear

    2026-09-25