Live·Open questions in longevity research

Aggregate or deposit

Cholesterol crystals

Cholesterol in a crystalline state, including stable seeds from which larger crystals can grow

Hypotheses on this target 1

Cholesterol crystalsClearance restoration. Hypotheses on this target 0Neutralisation. Hypotheses on this target 0Accelerated excretion. Hypotheses on this target 0Disaggregation. Hypotheses on this target 11Aggregation prevention. Hypotheses on this target 0
  • Clearance restoration
  • Neutralisation
  • Accelerated excretion
  • Disaggregation1
  • Aggregation prevention

Disaggregation1

  • Retained cholesterol crystal seeds may amplify skin inflammation after repeated damage and repair

    Where this hypothesis actsSkin undergoing repeated cycles of damage and repair, with crystal seeds persisting through treatment breaks

    What is proposedPrevent crystal seed formation or eliminate existing seeds

    With whatNot stated in the record

    HowSelectively dissolve crystals while preserving membrane cholesterol and cell viability, restoring the previous total cholesterol content in noncrystalline form

    Possible resultPossible prevention of the amplified inflammatory response during repeated exposure and stabilization of SPV_11

    2026-09-25