Rhythm or programme
Centriole duplication
The process by which cells duplicate centrioles, structures contained within centrosomes
Hypotheses on this target 1
Inhibition1
Activation
Function preservation
Feedback restoration
Rhythm restoration
Direct measurement
Inhibition1
Reprogramming may leave inherited extra centrosomes that undermine later repair
Where this hypothesis actsCycling aging human dermal fibroblasts exposed to repeated partial-reprogramming pulses
What is proposedPrevent inappropriate centriole reduplication while preserving necessary duplication
With whatNot stated in the record
HowSelective prevention or correction is proposed without a specified technique; necessary division and replacement must remain intact
Possible resultPossible reduction in segregation errors with preservation of competent replacement, matrix function and growth control
2026-10-10