Signalling pathway
Cell survival signaling
Signals that support the continued survival of cells
Hypotheses on this target 1
Inhibition1
Activation
Desensitisation
Function preservation
Feedback restoration
Rhythm restoration
Inhibition1
A pathogen-induced survival program explains persistence associated with faster repair
Where this hypothesis actsEpithelial cells with pathogen-induced growth-factor activation in the implicated infection subset
What is proposedInterrupt the survival signaling branch that supports pathogen persistence
With whatNot stated in the record
HowUse epithelial-specific signaling perturbations to separate survival signaling from migration, proliferation and restitution
Possible resultPossible reduction in pathogen persistence even when closure kinetics remain unchanged
2026-09-21