Signalling pathway
Cardiovagal baroreflex
A reflex linking changes in blood pressure to changes in cardiac slowing through vagal activity
Hypotheses on this target 1
Inhibition1
Activation
Desensitisation
Function preservation
Feedback restoration
Rhythm restoration
Inhibition1
Excessive heart-rate reflex correction may sustain instability after menopausal awakenings
Where this hypothesis actsAfter awakenings in a menopause-associated subgroup with excessive reflex correction
What is proposedPartially attenuate excessive cardiovagal reflex correction
With whatNot stated in the record
HowPartial, reversible attenuation in a preclinical causal arm; compare at matched initial awakening intensity, mean pressure and ventilation
Possible resultPossible shorter cardiovascular settling time and sleep re-entry latency despite reduced vagal HRV
2026-10-03