Specialised cell of an organ
Capillary mural cells
Cells attached to capillary walls whose contraction contributes to wall stiffness and resistance to collapse
Hypotheses on this target 1
Function restoration1
Reprogramming
Transplantation
Elimination
Proliferation
Function restoration1
Capillary contraction protects aging skin from vessel collapse and oxygen loss under pressure
Where this hypothesis actsPressure-exposed aged dermis under reduced intraluminal support
What is proposedSelectively increase mural-cell contraction to restore capillary wall stability
With whatNot stated in the record
HowModest selective activation in perfused microvascular constructs and animal skin with independently controlled inlet pressure and external loading; activation method unspecified
Possible resultPossible preservation of capillary patency, improved repair-site oxygenation and subsequent repair
2026-09-21