Rhythm or programme
Blood flow–sweat secretion synchrony
The timing relationship between changes in blood flow and pulses of sweat secretion
Hypotheses on this target 2
Inhibition
Activation
Function preservation
Feedback restoration
Rhythm restoration2
Direct measurement
Rhythm restoration2
Synchronizing local blood-flow and sweating rhythms may restore youthful skin heat loss
Where this hypothesis actsAged skin with misaligned vascular and secretory rhythms despite a preserved central thermoregulatory signal
What is proposedRestore synchrony between blood flow and sweat secretion pulses
With whatChange of environment or regimen
HowTime vascular pulses to coincide with secretion, keeping their integrated intensity constant and leaving mean secretion, mean blood flow and therapy carrier properties unchanged
Possible resultPossible restoration of heat loss and return of SPV_8 to the young reference range
2026-09-26
Loss of alternating activation across skin regions may destabilize heat loss
Where this hypothesis actsNeighbouring skin regions during repeated transitions between humid warmth and dry cool conditions
What is proposedRestore spatial alternation by staggering activation of neighbouring regions
With whatPhysical or surgical intervention
HowUse multizone stimulation with feedback to alternate activation across neighbouring regions while keeping the mean delay unchanged
Possible resultPossible stabilization of SPV_8 and smaller temperature excursions
2026-09-25