Live·Open questions in longevity research

Single microbe

Bacterial pathogens

Bacteria that cause infection

Hypotheses on this target 1

Bacterial pathogensInhibition. Hypotheses on this target 11Lower level. Hypotheses on this target 0Elimination. Hypotheses on this target 0Colonisation. Hypotheses on this target 0

Inhibition1

  • Clearing residual bacteria redirects protein-cutting enzymes toward host tissue

    Where this hypothesis actsResidual bacterial infection in a subset of older adults

    What is proposedSuppress bacterial pathogens to interrupt microbial substrate supply

    With whatSmall molecule

    HowUse non-lytic pathogen suppression with drug-only controls and matched released microbial products

    Possible resultExpected increase in host-protein cleavage after bacterial substrates disappear unless competing substrate is replaced

    2026-09-21