Regulatory protein
Antiproteases
Proteins that inhibit protease activity
Hypotheses on this target 1
Inhibition
Activation
Lower level
Higher level
Protection from degradation
Function restoration
Function preservation1
Function preservation1
Synchronizing skin sealing and deeper repair destabilizes recovery
Where this hypothesis actsExtracellular space during overlapping sealing-associated oxidant and remodeling-associated protease pulses
What is proposedPreserve protease-inhibiting activity during oxidant pulses
With whatProtein or peptide as the agent
HowUse an oxidation-resistant antiprotease matched to the wild-type inhibitor for baseline inhibitory activity and tissue concentration
Possible resultExpected abolition of the phase-dependent crossing of the stability boundary
2026-09-21