Immune cell
Antigen-presenting cells
Immune cells that present antigen and provide signals guiding adaptive immune responses
Hypotheses on this target 1
Activation1
Clearance restoration
Reprogramming
Adoptive transfer
Elimination
Immunosuppression
Population balance
Activation1
Bacterial signals can sustain immune protection after further antigen recognition stops
Where this hypothesis actsOlder-donor cultures after initial cognate priming and the first matched T–B interaction
What is proposedDeliver non-antigen-encoding bacterial RNA selectively to antigen-presenting cells
With whatTargeted delivery
HowAPC-targeted delivery of nonreplicating bacterial RNA to sustain the transient cytokine program after further cognate signaling is terminated
Possible resultPossible restoration of timely antigen-specific killing and functional antibody production
2026-09-21