Rhythm or programme
Antibody–effector co-occupancy
Simultaneous occupancy of the same target cell by antibodies and Fc-receptor-bearing immune effectors
Hypotheses on this target 1
Inhibition
Activation
Function preservation
Feedback restoration
Rhythm restoration1
Direct measurement
Rhythm restoration1
Antibodies and immune cells clear infection better when they act on the same target
Where this hypothesis actsOn the same infected cells during their surface-antigen exposure window
What is proposedRestore coincident antibody engagement and Fc-receptor-bearing effector occupancy
With whatChange of environment or regimen
HowVary schedules using a fixed mixture of autologous CTLs and Fc-receptor-bearing effectors, with matched antibody exposure, effector numbers, and component activity
Possible resultPossible stabilization of SPV_3 and improved viable-pathogen clearance
2026-09-21