Antibody
Antibodies
Molecules that bind antigens and can provide protective neutralization
Hypotheses on this target 3
Lower level
Protection from degradation1
Synthesis suppression
Neutralisation
Accelerated excretion
Protection from degradation1
Early neutrophil recruitment impairs clearance by chemically damaging protective antibodies
Where this hypothesis actsExtracellular antibodies in susceptible older-adult tissues exposed to neutrophil oxidants
What is proposedPreserve the opsonic function of local IgG
With whatProtein or peptide as the agent
HowRestrain early neutrophil recruitment; test causality by replacing damaged IgG with an equal concentration of intact, specificity-matched IgG
Possible resultPossible restoration of viable-pathogen clearance without reopening vessels or reducing recruitment
2026-09-21