Signalling pathway
Activator–inhibitor signaling
A signaling process combining local self-amplification with inhibition that spreads over a longer range
Hypotheses on this target 1
Inhibition
Activation
Desensitisation
Function preservation
Feedback restoration1
Rhythm restoration
Feedback restoration1
Self-organized danger and inhibitor signals sustain tissue injury after infection clears
Where this hypothesis actsAged tissue with persistent localized injury after independently verified pathogen elimination
What is proposedRestore stable signaling by extinguishing the spatial instability
With whatNot stated in the record
HowSpatially redistribute inhibitor at matched mean exposure, or neutralize extracellular injury cargo sufficiently to remove the instability
Possible resultPossible abolition of persistent injury, prevention of pattern reformation, and stabilization of SPV_5
2026-09-21