Mouse
Tabula Muris Senis
A mouse ageing atlas with gene-expression measurements from individual cells across tissues and age groups. A cell browser and processed data are available for independent analysis.
Example research question
Select liver immune cells and compare expression of a gene across age groups. Then check whether the difference holds across individual animals.
Conditions for comparison
These data concern mice. Account for animal count, sex, tissue and cell-isolation method. Cell count and independent animal count describe different aspects of the sample.
Human
Tabula Sapiens
An atlas of human cells across organs, including immune, epithelial, endothelial, neuronal and other cell populations. Explore measurements and export data through CELLxGENE.
Example research question
Compare expression of a selected gene in endothelial cells from different organs, then examine donor differences.
Conditions for comparison
The atlas is a reference for cell types and states. Ageing conclusions require checking donor ages, comparable samples and dataset version.
Fruit fly
Fly Cell Atlas
An adult fruit-fly atlas with single-nucleus and tissue data, including gut, heart and nervous system. The SCope browser and analysis files are available.
Example research question
Find gut cells expressing a selected gene. Use them as a starting point for an experiment that changes its activity.
Conditions for comparison
An adult cell map helps select cell types for research. Ageing comparisons require suitable age groups, and translation to humans requires independent validation.