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COMPANIESCompanies rated · 435 (no change)PROJECTSProjects rated · 70 (no change)CATALOGUE874 grants in catalogue · 19 open right nowPOWERED BYOpen Longevity · 501(c)(3) · Sherman Oaks, CACOMPANIESCompanies rated · 435 (no change)PROJECTSProjects rated · 70 (no change)CATALOGUE874 grants in catalogue · 19 open right nowPOWERED BYOpen Longevity · 501(c)(3) · Sherman Oaks, CA

Joe Betts-LaCroix

Betts-LaCroix helped define longevity biotechnology and co-authored guidance for bringing aging biomarkers into clinical research. His five papers have received 198 citations.

36 / 100entrepreneurscientistretro.bio/teamScoring AI engine · v0.8.0
Profile

Co-founder and CEO of Retro Biosciences, where he leads a portfolio of programs designed to reverse age-related disease and extend healthy human lifespan.

Role
entrepreneurhigh confidence

As co-founder and CEO of Retro Biosciences, he is building the operating company and therapy portfolio aimed at reversing age-related disease and extending healthy lifespan. This is the clearest and dominant evidenced longevity channel.

Joe Betts-LaCroix — verified profile

also: scientist

Dimension breakdown

This score rates longevity commitment only. The role tags above — scientist, investor, and the rest — say what this person is; we don't score those separately.

Future vision

6.0/ 10

Betts-LaCroix consistently advances an ambitious vision of extending healthy human lifespan by treating aging as a modifiable driver of disease. His public association with multiple rejuvenation approaches gives the vision some technical substance, but the evidence provides only one broad destination statement and no clear roadmap, timeline, success criteria, or sustained set of direct vision quotes.

medium confidence

Scientific impact

5.0/ 10

Primary bibliometrics show credible but not field-defining scientific influence: 198 citations across five works, with an h-index of 4 and one recent aging-biomarker paper already receiving 103 citations. The record suggests meaningful contribution to translational geroscience discussions, but the small corpus, largely collaborative authorship, modest h-index, and absence of clinical-trial or clearly attributable breakthrough evidence limit the score.

high confidence

Capital deployed

1.0/ 10

The dimension applies because Betts-LaCroix is a biotech founder, but the supplied evidence documents no investments, donations, or independently rated capital outcomes attributable to him. His leadership of Retro Biosciences and longevity-related scholarship establish field participation, not successful capital deployment under this rubric.

medium confidence

Strategic taste

3.0/ 10

Betts-LaCroix demonstrates a coherent longevity thesis and some early engagement with the case for healthy lifespan extension, but the evidence does not identify specific bets, their timing, contrarian rationale, catalytic importance, or field-level outcomes. Leading Retro's multi-program portfolio is relevant but insufficiently detailed to establish strong strategic taste.

low confidence

Field creation

4.0/ 10

Betts-LaCroix contributed to making longevity biotechnology more legible through collaborative publications defining the sector and proposing translational guidance. However, the supplied evidence does not independently establish that he created an organization, program, community, protocol, or funding path, so it cannot support a stronger field-creation score.

medium confidence

Bravery and conviction

2.0/ 10

The dimension applies, but the supplied evidence does not document any qualifying bravery exhibit. Betts-LaCroix publicly contributed to longevity advocacy and translation through research publications, but these sources do not establish a contrarian stance, career or financial sacrifice, a capacity-relative bet, persistence under serious criticism, or personal risk-taking.

low confidence

Multiplier effect

4.0/ 10

Betts-LaCroix shows modest second-order influence through widely cited longevity publications and participation in a broad industry collaboration, helping shape public and sector narratives. However, the evidence does not establish substantial talent attraction, capital mobilization, policy influence, founder creation, or follow-on projects attributable to him.

medium confidence
Vision

Destination

People want to live long, healthy lives.

[S1] Medium 2015

Path

No canonical quotes yet.

Publicly endorses AI-designed proteins can improve rejuvenation and replacement therapiesPublicly endorses Aging is a modifiable primary risk factor for disease
Strategy

Build biotechnology therapies that reverse age-related disease and extend healthy human lifespan.

Betts-LaCroix’s stated strategy centers on developing biotechnology therapies intended to reverse age-related disease and extend healthy human lifespan. His role leading a portfolio of programs at Retro Biosciences suggests a multi-program therapeutic approach, but no underlying strategy evidence was provided. Investment stage, geographic focus, risk appetite, and time horizon are therefore unknown. No evidence-backed investments, donations, notable bets, or collaborators were available, so none can be cited with [S#] references.

UnknownUnknownAge-Related DiseaseHealthy Lifespan ExtensionRejuvenation Biotechnology
Portfolio

Investments

No public rows yet.

Donations

No public rows yet.

Organizations founded

No public rows yet.

Scientific output
h-index4
Citations-
Papers0
Trials0
Connections

Companies

Collaborators and lineage

No public rows yet.

Criticisms