Direction
Measuring ageing
Biomarkers, ageing clocks and diagnostics that say how old a body really is
Companies
Companies in this direction
Ambition is what a company claims. Independent replication is what others have confirmed. Read the two columns together: the gap between them is where a promise runs ahead of a result.
| Company▲ | Ambition▲ | Independent replication▲ | Stage▲ | Headquarters▲ |
|---|---|---|---|---|
| Biotein Biotein is building a low-cost saliva test to measure protein markers of age-related cellular damage. | 5 | 0 | pre seed | – |
| Deep Longevity Deep Longevity provides AI-powered aging clocks and SaaS platforms for biological age prediction and personalized health insights. | 6 | 4 | acquired | Hong Kong |
| Edifice Health Edifice Health provides inflammatory health monitoring tests to help patients and clinicians manage systemic chronic inflammation. | 6 | 4 | – | San Francisco, California, United States |
| Generation Lab Generation Lab offers an epigenetic SystemAge test with personalized insights across 460 biomarkers and 21 organs and systems. | 8 | 1 | – | San Francisco, California, United States |
| Life Length Life Length measures aging and disease biology using telomere, telomerase, oxidative stress, NAD+, and single-cell biomarker diagnostics. | 3 | 2 | – | Madrid, Spain |
| My Aging Tests MyAgingTests provides epigenetic biological age testing and evidence-backed tools for longevity interventions. | 6 | 5 | – | United States |
| Sapere Bio Sapere Bio provides biomarker testing for longevity, immune resilience, cellular senescence, and athletic performance. | 6 | 3 | – | Raleigh-Durham, North Carolina, United States |
| Tally Health Tally Health provides epigenetic age testing, longevity supplements, and personalized insights designed to improve healthspan and longevity. | 6 | 4 | – | United States |
| Vero Biosciences Vero uses proteomics and machine learning to measure organ-level biological age from a single blood draw. | 7 | 1 | – | United States |
Projects
Projects in this direction
| Project▲ | Science▲ | Breakthrough▲ | Investment case▲ |
|---|---|---|---|
| CHANGS CHANGS is a newly announced 2025 Chulalongkorn University-BGI collaboration in Thailand focused on healthy aging, using omics and AI-based bioinformatics to analyze elderly health, collect volunteer samples and clinical data, and reportedly build outputs such as multi-omic aging measures and organ-aging models. The evidence supports that the project exists and has institutional backing, but not that it has yet produced validated biomarkers, intervention results, or clinical utility. | 38 | 37 | 38 |
| Japan Longevity Consortium Japan Longevity Consortium is a Japan-based academic consortium led from Juntendo University that is promoting a biomarker-guided, multi-component “Scientific Zen” healthspan program combining washoku-style diet, mild fasting, exercise, yoga/breathing, TEAS, far-infrared therapy, supplementation, and gut-focused management to improve cognition, immune function, and muscle function. The strongest signals are a senior university team, XPRIZE Healthspan Top 40 semifinalist status, and self-reported preliminary observational findings on epigenetic-age and autonomic outcomes; the main constraint is that the core efficacy claims are currently presented mostly on the consortium’s own site or institutional announcements, with limited methodological detail and no clearly linked peer-reviewed validation of the full program. | 42 | 42 | 55 |
People
People in this direction
- Aubrey de Greypopulariser · through Human Longevity Inc.
SENS Foundation founder and longevity advocacy pioneer.
- George Churchscientist · through Generation Lab
Led and founded major synthetic biology and genomics efforts with public work on aging reversal, gene therapy, and longevity biotechnology companies including Rejuvenate Bio.
- Alex Zhavoronkovpopulariser · through Deep Longevity
- Steve Horvathscientist · through My Aging Tests
- Vadim Gladyshevscientist · through Deep Longevity
Redox biologist mapping the mechanisms and signatures of aging
- Eric Verdinscientist · through Edifice Health
- Tony Wyss-Corayscientist · through Vero Biosciences
Neuroscientist decoding how systemic aging affects the brain
- David Sinclairscientist · through Tally Health
- Kelsey Moodyentrepreneur · through Biotein
Drug-development entrepreneur building an integrated longevity biotech platform
- Peter Diamandisentrepreneur · through Human Longevity Inc.
Chronology
What happened, and when
Hypotheses
Hypotheses under test in this direction
Published by the Omega Point engine and tagged to this direction by a classifier; the gap each one attacks is named under it
Forecasts